Slow-release tablets Slow-release tablets are made of special high-density material with a skeleton, in which the drug is encapsulated and released slowly, and if crushed, the structure of the skeleton will be damaged, affecting the efficacy of the drug. Therefore, should not be crushed to take. ② controlled-release tablets controlled-release tablets are relatively high requirements for drug release preparations, so most often seen in cardiovascular preparations, which has a relatively constant release dose per unit of time to maintain a constant blood concentration, the effectiveness of a more durable. After the tablet is divided, the controlled-release membrane or the controlled-release skeleton is destroyed, and the drug will be released rapidly, so it can not achieve the purpose of controlled release, and sometimes it can also cause a sudden rise in the concentration of the drug in the body, resulting in drug intoxication. Double-layer sugar-coated tablets such as multi-enzyme tablets are double-layer sugar-coated tablets containing three kinds of digestive enzymes (amylase, pepsin, pancreatic enzymes). The outer layer is general enteric coating, amylase and pepsin are in the outer layer of the tablets, which can play the role of digestive aid in the stomach. Pancreatic enzymes, on the other hand, need to function in the alkaline intestine and are therefore encapsulated in the inner layer of the tablets. If the tablet is crushed, it loses its protective effect, especially if the pancreatic enzyme powder remains in the mouth, it can damage the oral mucosa and even cause serious oral ulcers. ④ Enteric tablets, that is, in the ordinary tablets wrapped outside a layer of coat, this layer of coat is dissolved only when it reaches the intestine. Therefore, this kind of tablet must be swallowed whole, if crushed and taken will not only reduce the efficacy of the drug, but also cause side effects.