The pharmacist should clearly explain the usage, dosage, contraindications and precautions of the drugs dispensed to the patients in simple language or words when dispensing the drugs, because the sticker cannot replace the drug delivery: Notes on topical preparations: 1, boric acid powder: a bag of boric acid powder is 50g, a dosage of 5g, each 5g of boric acid powder diluted with 1000ml of warm water to avoid the concentration of boric acid solution is too high. 2, sodium bicarbonate powder: a bag of sodium bicarbonate powder is 100g, a dosage of 10g, every 10g sodium bicarbonate powder diluted with 100ml of warm water, to reach a concentration of 10% is more appropriate. 3, potassium permanganate topical tablets: should be prepared in the ratio of 1:5000 aqueous solution for external use, can not be taken orally, at the same time should also be entrusted to patients to avoid burns due to high concentration of aqueous solution, generally light red can be. 4, rehabilitation new liquid: can be taken orally, but also can be used externally. Therefore, it is necessary to judge whether the medication is reasonable according to the clinical diagnosis or communication with the patient. 5.Ventolin/Sulidex inhaler (β2 agonist): prone to nausea, dizziness and palpitations. Use with caution in patients with hypertension and hyperthyroidism. Long-term use may lead to drug resistance and reduced efficacy. 6, Co-corticosteroid / Burkner / Budesonide inhaler (glucocorticoid): To prevent respiratory fungal or viral infections and hoarseness, rinse your mouth after each dose, so that the drug does not remain in the throat. 7. ipratropium bromide inhaler (M receptor blocker): Use with caution in patients with glaucoma tendency and prostatic hyperplasia, and a few patients have dry and bitter mouth. Precautions for oral medication: 1. Antihistamines: have the side effect of drowsiness, and cannot drive, work at height or perform other delicate and dangerous operations after taking the medication. In addition, cimetidine is more effective after meals than before. It is generally advocated to take H2 receptor blocking drugs before bedtime (to inhibit gastric acid secretion at night, reduce the stimulation of gastric acid on the ulcer surface and facilitate the healing of ulcers. 2.Sulfonamides (compound sulfamethoxazole): When applying uric acid-removing drugs to treat gout, you should drink more water so that the daily urine volume reaches more than 2,000 ml, and you should alkalize the urine to prevent uric acid from forming stones in the urinary tract during the discharge process. It should also alkalize the urine to prevent uric acid from forming stones in the urethra. 4.Glucose-lowering drugs Glimepiride: given immediately before breakfast or the first main meal Gliclazide: half an hour before meal Glipizide: half an hour before meal Repaglinide: taken 0-30 minutes before main meal, mostly 15 minutes before meal Metformin: taken at meal time, if there is stomach discomfort can be changed to after meal Acarbose: swallowed whole immediately before meal or chewed with the first few bites of food Pioglitazone: taken with 5, gastroenterology drugs: Omeprazole magnesium: must be swallowed whole, not chewed, should be avoided with oral imidazole antifungal drugs such as itraconazole, fluconazole taken at the same time. Can be taken with bedtime. Aluminum phosphate gel: gastritis, gastric ulcer half an hour before meals, duodenal ulcer should be taken 3 hours after meals or when pain. Magnesium aluminum carbonate chewable tablets: 1-2 hours after meals, before bedtime or when the stomach is upset, and need to be handed to chewed to take. Sodium bicarbonate: should be taken l-2 hours after meals and at bedtime, no drugs should be taken within l-2 hours after oral administration of this product Mosapride: 15-30 minutes before meals, peak blood concentration can be reached in 15-30 minutes Polyethylene glycol electrolyte: good to be taken at longer intervals with other drugs (at least 2 hours) Loperamide: not suitable for children under 5 years old, prohibited in acute bacillary dysentery with high fever and purulent stools Loperamide should be used with caution in elderly patients suffering from constipation. Take half an hour before meals or on an empty stomach. Montmorillonite: for patients with esophagitis, take after meals; for other patients, take between meals, immediately in case of acute diarrhea, and add the first dose of elimocadotril: take orally three times a day, for no more than 7 days. Compound digestive enzymes: take after meals. It is not suitable to be taken with acidic drugs, and the efficacy of the latter is reduced when combined with acarbose. Bifidobacterium trisporium: Take with warm water half an hour after meal, infants can peel off the capsule and pour out the powder and take with warm water. Clostridium Typhimurium: Take it with warm water half an hour after meal, avoid taking it together with antibacterial drugs, if you have to take it, you have to stagger it by 2 hours. 6. Adjuvant medicine for hepatobiliary diseases: Compound glycyrrhizin: Take after meal, senior patients need to be cautious in administration, because of high incidence of hypokalemia, attention should be paid. Compound Azinomide: Take after meals. Contraindicated in patients with hepatic dysfunction, acute hepatitis, biliary obstruction, avoid taking with alkaline drugs. Adefovir/Lamivudine: can be taken before or after meals, patients are advised not to stop the drug on their own, and need to be monitored regularly during treatment 7, micronutrient class: iron calcium: deca-iron chewable tablets, calcium chewable tablets of vitamin D are well absorbed after meals, hand over 1-2 hours after meals to chew and take, in addition, the combination of iron and tea in the tannin will reduce the effectiveness of iron, you can not drink tea during taking the drug. Folic acid tablets: iron deficiency anemia requires folic acid supplementation, but folic acid is divided into two kinds, one high dose for anemic patients and another for pregnancy. If a small dose of folic acid is not used as prescribed by the doctor, it will reduce the effectiveness and delay the good treatment time. Vitamin E capsules: cerebral vascular sclerosis and cerebral blood supply deficiency of male patients who refuse to take the drug instructions for the treatment of habitual abortion, then it is extremely detrimental to the treatment of patients. 8, cardiovascular and cerebrovascular class: Digoxin tablets: some drugs are close to the therapeutic dose and poisoning dose, more should be executed according to the doctor’s orders. For example, digoxin used for the treatment of heart failure, some patients do not adhere to the regular treatment, although the symptoms improve, but the course of treatment is not enough, think that the disease has been cured Potassium chloride extended-release tablets: potassium chloride due to irritation, such as not according to medical advice and reasonable use of drugs, will damage the gastric mucosa affect the normal diet or cause hyperkalemia. Propafenone Tablets: Severe obstructive pulmonary disorders and marked hypotension are prohibited. Amiodarone Tablets: The half-life of this product is long, so when switching to other antiarrhythmic drugs after discontinuation of the drug, attention should be paid to the interaction, and frequent attention should be paid to the changes in heart rate and blood pressure, such as the discontinuation of the heart rate less than 60 times/min. Felodipine extended-release tablets: Take on an empty stomach before meals, as the bioavailability of this product is affected by diet. Metoprolol: Food can increase the plasma concentration of this product taken orally up to double that taken on an empty stomach. Carvedilol: taken with food, when taken with food, its absorption is slowed down, but there is no significant effect on bioavailability, and it can reduce the risk of causing postural hypotension Captopril: food in the stomach can reduce the absorption of this product by 30% to 40%, so it is advisable to take the drug one hour before meals. Fenofibrate: Taking with food can increase the absorption of fenofibrate. To reduce stomach discomfort, it can be taken with diet. Gemfibrozil: Lovastatin/simvastatin/atorvastatin calcium: once a night in a single dose. Spironolactone: taken at 10 a.m. It should be taken with a meal to reduce gastrointestinal reactions and possibly improve the bioavailability of the drug. Furosemide: taken at 10:00 a.m. to avoid an increase in the number of urinations at night. Nitroglycerin tablets: should be taken sublingually to avoid first-pass effect. Earth kinase: must be taken before meals, with bleeding tendency to be used with caution. 9, antipyretic and analgesic: diclofenac sodium: taken after meals, this product may induce or aggravate gastrointestinal bleeding, ulcers and perforation in the elderly. Use with caution in elderly patients taking diuretics or with extracellular fluid loss. Compound acetaminophen: prohibited during pregnancy and lactation, in addition to the liver damage is relatively large, such antipyretic and analgesic antipyretic drugs should be explained clearly “if necessary”, do not let some patients anxious to reduce fever in a short period of time repeated medication, causing profuse sweating or even deficiency. The patient should be told to take it orally when the temperature exceeds 38.5°C. If the fever persists, the drug can be repeated once at intervals of 4 to 6 hours. Ketoprofen: It can be taken after meals. Absorption is slowed down when taken with food and milk, but absorption is still complete and gastrointestinal irritation can be avoided. 10, respiratory medicine: compound licorice combination: containing licorice fluid infusion, should be used with caution in patients with hypertension, licorice can easily lead to water and sodium retention, which will increase blood pressure. Diabetic patients should be prohibited, because licorice has the effect of raising blood sugar, so it is important to strictly follow medical advice. Ambroxol hydrochloride: Take it after meals, with the instruction to avoid taking powerful cough suppressants together to avoid diluting the sputum and blocking the airway. Theophylline extended-release tablets: should be taken at night at 8-9 o’clock, as asthma often attack in the early morning or aggravated in the early morning, the time to take the drug is good to choose at 8-9 o’clock in the evening. 11, the nervous system: carbamazepine tablets: large doses can cause atrioventricular block, so the dose should be controlled according to medical advice. Fenazepine tablets: long-term large amounts of drugs can cause delayed dyskinesia, dosage and treatment should be strictly in accordance with medical advice. Paroxetine tablets: The dose should be gradually reduced and not stopped abruptly. It is better to take it in the morning. Flunarizine capsule: strictly control the drug dose, when the application of maintenance dose does not achieve therapeutic effect or long-term application of extrapyramidal symptoms, the dose should be reduced or discontinued. 12, antibiotics: Metronidazole, cephalosporins and other antibacterial drugs can occur with ethanol disulfiram-like reaction, resulting in the accumulation of ethanol in the body and poisoning, to give up alcohol or do not drink alcoholic beverages during the use of drugs. Cefuroxime: This product should be taken after meals to increase absorption, improve blood concentration and reduce gastrointestinal reactions. Cefadroxil: This product should be taken on an empty stomach, but those whose gastrointestinal tract reacts strongly to cefadroxil should take it about one hour after meals. Amoxicillin Clavulanate Potassium: It can be taken on an empty stomach or after a meal, while dispersible tablets can be taken after dissolving the tablets with water. Penicillin V potassium tablets: Food can reduce the absorption of this product and can be taken on an empty stomach. Doxycycline hydrochloride: eating has little effect on the absorption of this product, and taking it after meals can reduce the gastrointestinal reaction. Roxithromycin: Eating can reduce the bioavailability by about half. Clarithromycin may be taken on an empty stomach: food may slightly delay absorption, but does not affect bioavailability. It can be taken on an empty stomach Norfloxacin: prohibited under 18 years of age, taken on an empty stomach with 250ml of water. Levofloxacin: taken after meals, and sunlight should be avoided with quinolones to prevent photosensitivity reactions. Sparfloxacin: concentration-dependent drug, better to be taken in one dose within the daily limit. Isoniazid: nighttime dosing is better. Rifampicin: Take on an empty stomach to ensure good absorption, or after eating if gastrointestinal irritation occurs. Itraconazole: High bioavailability when taken immediately after a meal. Fluconazole: Since the half-life is greater than 24h, it must be taken strictly in accordance with medical advice, otherwise it is easy to cause drug accumulation and poisoning. 13, antiviral drugs (acyclovir): in order to reduce the damage of acyclovir on kidney function, you need to drink more water during the medication. 14, anorectal drugs: Diosmin: divide the daily dose into two equal doses at lunch and dinner 15, osteoporosis drugs: alendronate sodium tablets: at least 30 minutes before breakfast on an empty stomach with 200ml of warm water. At least 30 minutes after medication before eating. 16, adrenal corticosteroids: prednisone tablets: 6-8 a.m., in the peak of secretion once a dose of better results, taken after meals to avoid gastrointestinal reactions. 17, cold medicine: compound pseudoephedrine extended-release capsules: should be given once every 12 hours, and should not exceed 2 capsules in 24 hours. Although pseudoephedrine hydrochloride is an epinephrine-like drug, with contraction of the upper respiratory capillaries, but for patients with heart disease, hypertension and other diseases in the selection of the drug must not be self-judgment medication, must be used under the guidance of a doctor to reduce the possibility of danger. It is not possible to give specific explanations to every patient. At the same time, pharmacists should not make excessive exaggerations and propaganda about the efficacy of drugs, nor should they overemphasize the uncommon adverse reactions, nor should they explain too much about the price of drugs.