For various reasons, the use of antimicrobials in our country is seriously disordered, although the health sector has carried out a variety of measures to regulate, but due to the huge profit output of China’s pharmaceutical industry, as well as the people’s understanding of the misconceptions of the antimicrobials, the management of antimicrobials has not seen any significant results, so on and so forth, more and more drug-resistant bacteria emerge one after another, more and more bacteria are resistant to a variety of antimicrobials, the pace of human development of antimicrobials has been unable to catch up with the speed of bacteria resistance, when one day there is no real infection available, we physicians can not do anything about it. The pace of antimicrobial development has not been able to catch up with the speed of bacterial resistance, and when one day there is no antimicrobial available for a real infection, there is nothing we physicians can do. Therefore, it is recommended that: 1. Antibacterials should no longer be used for the common cold; if this can be done, the amount of unregulated use of antimicrobials will decrease dramatically. 2. 2, ordinary not serious enteritis also do not easily use antimicrobials, many enteritis is not caused by bacterial infection. 3, the people should not bring their own antimicrobials at home. 4, do not go to the hospital on their own to name the application of antimicrobial infusion treatment, especially no infection based on the temporary application of antimicrobials once. 5, do not buy antimicrobials at the pharmacy. If you want to apply antimicrobials, please ask whether there is any evidence of bacterial infection.