The goal of condyloma acuminatum treatment is to remove as many visible warts as possible and reduce recurrence. Current treatments include topical medication, physical therapy, photodynamic therapy, surgery and immunotherapy. 1, local drug treatment Treatment drugs are footleaf toxin, footleaf ester, trichloroacetic acid, 5-FU cream, 5% imiquimod cream, etc. The local drug treatment is suitable for male and female external genital parts of the condyloma acuminata, and warts are not large CA treatment, this treatment method is convenient, patients can treat themselves at home, but the use of appropriate methods, and need to pay attention to the side effects of drugs and adverse reactions. 2, physical therapy and photodynamic therapy There are laser, freezing, microwave and photodynamic therapy. Most CA can use physical therapy, but laser, freezing, microwave and other physical therapy can quickly get rid of warts, but can not effectively eliminate HPV subclinical infection and latent infection, so the treatment is not only easy to recur, and this treatment is painful, easy infection and scar formation and other disadvantages. 3, surgical treatment for the larger warts, surgical excision effect is better, but surgical excision treatment invasive, easy to form a scar after surgery. 4, immunotherapy Interferon, transfer factor and thymidine have the role of regulating the body’s immunity, can be used as an adjuvant treatment of CA. In short, the individualized choice of acromegaly treatment can achieve better results and reduce the incidence of adverse reactions, but regardless of what therapy is taken, there is the possibility of recurrence, it is best to use combined therapy to reduce the recurrence rate of CA.