If chromosomal abnormalities are detected during pregnancy, it is easy to affect the fetus and the probability of congenital dysplasia is relatively high. It is recommended to cooperate with the doctor to do 4D ultrasound examination in time to observe whether the fetus has congenital developmental abnormalities. If no abnormality is found in the ultrasound examination, it is better to cooperate with the doctor to do non-invasive amniocentesis to check whether there is any abnormality in the fetal DNA and terminate the pregnancy in time to avoid congenital developmental abnormalities or fetuses with congenital diseases. Chromosomal abnormalities have a higher probability of fetal abnormalities if they are present before pregnancy. If the abnormalities occur after pregnancy due to some factors that cause genetic mutations, they have little effect on the fetus. Regular prenatal checkups and 4D ultrasound are needed under the guidance of doctors to confirm whether the fetus is developing normally, which can avoid congenital developmental malformations and other conditions.