Chromosomal abnormalities do not necessarily have a 4D presentation. If the above abnormalities occur due to chromosomal abnormalities, 4D ultrasound can be used to diagnose and visualize the abnormalities, but 4D ultrasound cannot diagnose chromosomal abnormalities.
If the child has no abnormalities, the abnormalities cannot be visualised in 4D ultrasound, or only restricted fetal growth can be detected. Therefore, if chromosomal abnormalities are suspected, karyotyping, fluorescence in situ hybridisation, and microarray comparative genomic hybridisation techniques can be done for diagnosis.