Children love to play, always inattentive will cut the skin, if not pay attention may lead to infection. This is a common phenomenon in life, and few people pay attention to it, thinking that a little bandage will do, but do not know that regular skin infections may lead to the occurrence of acute nephritis. The most common kidney disease in the clinic is glomerulonephritis, which is short for glomerulonephritis, an immune disease to streptococcal infection. Acute nephritis in children is a common disease in children, with a high incidence, especially septic skin infections, are prone to secondary renal immune damage and acute nephritis. Skin and kidney can not only affect each other, but also kidney diseases caused by skin diseases, which are mainly pyoderma, skin trauma and pruritic skin diseases, including impetigo, folliculitis, boils, eczema, papular urticaria, insect bite dermatitis, tinea pedis and other diseases. When the body’s resistance is reduced, such as scratching after the skin breaks, Staphylococcus aureus, streptococcus and other purulent cocci take advantage of the situation, if not treated in time, the purulent cocci easy to invade the kidneys, causing glomerulonephritis. Acute nephritis in children occurs mostly in preschool children, and is especially common in children over 3 years of age, who are usually prone to pediatric nephritis after 2-3 weeks of skin infection. Due to its various manifestations without pain or itching, parents who do not carefully observe the changes in their children may delay the condition. In general, acute nephritis is often preceded by pioneering infections such as acute tonsillitis and cutaneous pustulosis. The function of the kidneys is to constantly filter and remove waste products from the body. If the kidneys cannot remove these wastes properly, hematuria and proteinuria are produced. However, if handled properly, more than 95% of acute nephritis can be treated effectively, but prevention is especially important. Therefore, parents should be careful, do not be careless and delay your child’s condition and miss the best time for treatment.