The pathogenesis of reoccurrence is closely related to all the five organs, but the heart is the core, and fundamentally the mechanism is always the change of heart fire. Since the heart is a fire organ and the sun of yang, heart fire is prone to hyperactivity and evil fire, and deficiency and deficiency, and it is difficult to self-regulate the surplus and deficit, and then the function is disordered. Of course, the liver is the main blood collector and can regulate the amount of circulating blood; the spleen is the main transporter and is the basis of the postnatal period, serving the water and grain essence that create blood, and the spleen is the main blood regulator, working with the heart to complete the normal operation of blood. The kidneys are the foundation of the first heaven, the main reservoir of essence, which can transform the blood; the lungs face the hundred veins, the main zongqi, and distribute blood around the body. Other organs, such as the six internal organs and the Qi Heng’s internal organs, are also directly and indirectly related to the production and function of blood to a certain extent, but the liver, spleen and kidney are always more closely related. In terms of blood production and quality, the heart is the key. The “blood evidence” contains: “the heart can do things, and the main blood, and the heart orifice in a few points of blood is the most delicate of the blood, is the source of blood, but also out of the God of the abyss.” In terms of its quantity, it is closely related to the spleen because the spleen is responsible for transporting and transforming the essence needed to produce blood. ”Based on the weakness of the lesser fire of the heart, which is the main source of blood production, the fire takes advantage of the deficiency and enters the Shaoyin heart vein, forming the general pathogenesis of aplastic anemia in Chinese medicine. Fundamentally speaking, aplastic anemia is mainly due to deficiency, but most of the deficiency is caused by actuality. The formation of aplastic anemia is mostly due to deficiency, which leads to the internal accumulation of voodoo fire, depletion of blood and gradual development. The cause of this is that the vicious fire damages the spleen and the spleen’s yang, and the blood loses its source and is insufficient to produce blood. Once the blood supply is insufficient, first of all, it will aggravate the vasefire, resulting in the fire evil blazing, forcing the blood to move, resulting in bleeding; secondly, the vasefire will flow and spread to the sympathetic yin, resulting in fever. Once again, the decoction of Yin consumes Blood, forming volatile phlegm, volatile stasis, and phlegm stasis blocking the ligaments, resulting in lesions in the heart and lung organs and limbs and meridians; worse, wind is generated from within, and wind and fire incite each other, resulting in stroke and tremor. If the disease is prolonged, the fire will eat the qi, the yang will be deficient, the yin will be exhausted and the fluid will be withered, the yin and yang will be deficient, and even the yin and yang will leave the critical evidence, and the prognosis is not good. Generally speaking, the initial point of the pathogenesis of blood disorders is that volatile fire is latent in heart Shaoyin, after which it goes out to the pericardial sympathetic meridian and then to the lung Taiyin meridian, which is in line with the general characteristics of the transmission of volatile fire and is called downward transmission and vice versa. This kind of transmission from the top to the bottom is called reverse transmission, and the opposite is smooth transmission. However, transmigration between the meridians is also seen, often reflecting sudden changes in the disease. In conclusion, the volatile fire basically changes in the order of Shaoyin, Conjunctive Yin, and Taiyin in remittent disease.