After pregnancy, cholesterol in the blood and bile of pregnant women increases, and the rate of gallbladder emptying is slow, and the ratio of cholesterol to bile salts in bile changes, causing cholesterol to deposit and form stones, which can trigger cholecystitis. Acute cholecystitis in pregnancy can occur in all stages of pregnancy, but is more common in late pregnancy and puerperium, with an incidence of about 0.8 per 1000. Most acute attacks of cholecystitis are characterized by severe pain in the right upper abdomen, which is persistent and often intensifies paroxysmally. A significant number of patients have radiating pain in the right shoulder or right upper back, accompanied by fever, nausea, vomiting, etc. Jaundice is present in those with gallbladder and bile duct obstruction. The principle of treatment for acute cholecystitis in pregnancy is conservative treatment based on proper diet control, relief of symptoms with antibiotics to prevent infection, elimination of complications, and surgery if necessary. Conservative treatment specific measures: 1, control diet: severe patients should be fasted, mild patients with symptom onset, fat-free diet should be prohibited, such as in remission can be given high sugar, high protein, low fat, low cholesterol diet. Appropriate fluid supplementation, vitamin supplementation, correction of water and electrolyte imbalance. 2, symptomatic treatment: available antispasmodic and analgesic agents such as atropine or pethidine intramuscular injection. Methadone, indomethacin, etc. also have antispasmodic and analgesic effects and can be used appropriately. During the period of symptom relief, oral choleretic drugs such as dehydrocholic acid and ursodeoxycholic acid can be used to relax the sphincter of Oddi and promote the emptying of the gallbladder. 3, anti-infection treatment: broad-spectrum antibiotics cephalosporins should be used in the bile 4 to 12 times higher than the concentration in the blood, and no adverse effects on the fetus, should be the first choice, where the concentration of cefoperazone in the bile is 100 times higher than the blood concentration is an effective antibiotic for the treatment of serious biliary tract infections. Unless the condition is critical, such as in the case of perforated gallbladder or diffuse peritonitis, surgical treatment should be promptly performed. In general, surgery should be chosen in the middle of pregnancy, when the miscarriage rate is about 5%, lower than in other periods of pregnancy. If the expected date of delivery is near, it is best to wait until after delivery to perform surgical treatment. After surgery, fetal preservation treatment should be given.