World Mental Health Day, celebrated on October 10 every year, reminds people to pay attention to mental health. The latest study of the famous medical journal “The Lancet” points out that there are about 450 million people with mental illnesses in the world, and about 173 million people in China suffer from mental illnesses, of which 158 million people have never received professional treatment. Experts pointed out that: for mental illness, individuals should attach great importance to actively check; for serious mental illness, we should dare to “lighten up”, that is, actively accept treatment. Mental illness and physical disease clinical manifestations are different; often neglected or not timely treatment, which may lay a disastrous hidden danger. Experts pointed out that the early symptoms of mental illness are sleep disorders, emotional anomalies, irritability, persistent fatigue, generalized pain and many other manifestations, these are the body sends out a “spiritual alarm signal”; serious cases even hallucinations, delusions, violence, injury, suicide and other behaviors. In a variety of mental illnesses, depression and anxiety disorders are relatively common, but also “difficult”, often accompanied by the occurrence. The number of suicide deaths caused by depression even exceeds the number of traffic accident deaths. More serious mental illnesses are schizophrenia, mania and bipolar disorder. These illnesses often cause serious harm to individuals, families and society, affecting the stable life of families and society. In the face of serious mental illnesses, many people often do not dare to seek medical treatment because of the shame of getting sick or the fear of being looked down upon, or even if they do, they cannot take medication on time and as required. A small number of patients have difficulties in controlling their intractable symptoms even if they take medication for years, which puts a heavy pressure and burden on the family and the society. Experts believe that patients with drug-refractory mental illnesses, such as schizophrenia, depression, anxiety disorders, bipolar disorder, alcohol addiction or drug dependence, should actively seek surgical treatment to remove intractable symptoms as soon as possible, so that they can regain their social functions as soon as possible. In recent years, stereotactic neuromodulation surgery technology has been widely used, which makes the treatment of severe mental illnesses simple and easy with its minimally invasive, precise, safe and effective features. Its core idea is based on modern psychosurgery theory, that is, some neural nuclei in the cerebral neural circuit control the human body’s thinking, emotion and volitional activities, and once abnormalities occur, they will cause mental illnesses; after MRI, CT, DTI and other examinations of the head, it can accurately locate these neural nuclei, and the use of radiofrequency or DBS technology can effectively regulate the function of these neural nuclei, so as to control the abnormal psychiatric symptoms. Symptoms. Functional neurologists remind that for severe, drug-refractory psychiatric disorders, comprehensive clinical evaluation and systematic physical examination are crucial before implementing surgical treatment.