In outpatient clinics and wards, patients often ask whether taking psychiatric drugs will affect their pregnancy, fetus, intelligence, etc. It is difficult to answer this question correctly because there are no large samples of patients who have been tested on pregnant women. It is difficult to answer this question correctly because there are no large samples of drugs tested on pregnant women, and there are only results of individual patients using the drugs. In our clinical work, some patients who became pregnant while taking the medication until they gave birth had no problems with their children, but that does not mean that the medication has no effect on all who take it. To date, no psychotropic medication has been approved by the U.S. Food and Drug Administration for use in pregnancy. Drug-induced malformations account for only 5% of all fetal malformations. The main risks of psychotropic drugs to the fetus include congenital malformations, perinatal syndromes, and long-term psychotropic behavioral sequelae. But clinically there are some psychiatric patients taking drugs during pregnancy, the fetus born completely normal, so can not be generalized. Psychiatric patients who stop taking medication may lead to a relapse of the disease, and the period of onset is not favorable to the development of the fetus. Most psychiatric drugs belong to category C: it is uncertain whether they cause fetal abnormalities in the fetus. A few drugs belong to category D: may cause some fetal malformations. Clozapine belongs to category B: there is no evidence of fetal effects. None of the current antipsychotics are in Class A. General principles of drug use in pregnancy: 1. No drug is absolutely safe for the fetus. It is important to weigh the pros and cons by giving full consideration to the consequences of the mother stopping the medication or not treating, such as ‘relapse, impulsivity, aggression, suicide, etc.’. 2, try to avoid the use of drugs that may have a risk of teratogenicity, such as drugs in class D and other drugs. Especially in the first three months of pregnancy to be particularly cautious, can not be used drugs do not use. 3, the use of drug metabolism has a clear description of the drug. 4, drug metabolism during pregnancy is significantly slower than non-pregnancy, as far as possible, the use of the lowest effective dose, as short as possible, if necessary, blood concentration monitoring. 5.According to the different degree of influence of drugs on the fetus, choose the drugs that have the least influence on the fetus, and avoid the combination of drugs if they can be used alone. 6, the dose of the drug should be the smallest effective dose, the time as short as possible. Especially in the prenatal period, the dose should be reduced, because the drug may accumulate in the fetus, resulting in neonatal sedation effect. If you decide to take drugs during pregnancy, you should choose the stable period of the disease, under the guidance of the doctor to use drugs, choose relatively no or small effect on the fetus of the drug, regular examination of the fetus, do not blindly optimistic, and do not have to spend the whole day worrying about the drug will affect the fetus. The postpartum period is a period of high incidence of mental illness, and the dosage of medication should be increased in time to prevent relapse.