Ductal adenocarcinoma of the pancreas is divided into the head of the pancreas and the tail of the pancreas, but of course the treatment is similar. If the tumor is not surgically resectable, we will do radiotherapy or chemotherapy, but of course, radiotherapy and chemotherapy are generally required to obtain a pathological diagnosis. Radiotherapy is mainly for locally progressive pancreatic tumors that invade blood vessels and cannot be radically resected, and radiotherapy can be considered for such patients. For patients with inoperable tumors in the middle and late stages, chemotherapy can often be administered, and it is also necessary to obtain a medical examination. Chemotherapy can be combined with radiotherapy, we call it synchronous radiotherapy, chemotherapy drugs include gemcitabine, 5-fluorouracil, cisplatin, protein-bound paclitaxel, oxaliplatin and some other drugs.