Swollen feet are a symptom of many diseases. In addition to treating the primary disease with medication to eliminate the trigger for swollen feet, diuretics can be used to reduce fluid in the interstitial spaces of the tissues and achieve a reduction in swelling. Drugs such as furosemide, etanercept, bumetanide and hydrochlorothiazide, indapamide, etc., spironolactone and aminopterin are effective diuretics to reduce swelling, and the specific drugs should be used under the guidance of a doctor.