Chronic hepatitis B has become a public health problem that seriously jeopardizes the health of our people, and long-term antiviral treatment is the core of chronic hepatitis B treatment. In this long-term struggle with the hepatitis B virus on the journey, hepatitis B patients need to go through a variety of trials and tribulations. In order to fight the virus with half the effort and not to take a crooked or forked path. Hepatitis B antiviral treatment process needs to pay attention to the following things: antiviral to pay attention to the timing, the time is not yet do not participate. Not all people infected with hepatitis B virus need antiviral treatment, some hepatitis B virus carriers may not develop hepatitis throughout their lives, this part of the people do not need antiviral treatment; There are also some patients, although the virus level in the body is very high, but alanine aminotransferase (ALT) has always been normal, that is to say, the hepatitis B virus and the body’s immune system is in ” Do not interfere with each other, peaceful coexistence” period, the body’s immune system has not launched an attack on the virus, if the immune system and the hepatitis B virus does not appear “melee”, the patient can be a little bit calm, wait for the right time, at this time only need to regularly do a good job of monitoring and observing the hepatitis B virus and liver function is not appearing At this time, we only need to do regular monitoring to observe whether the hepatitis B virus and liver function are “different”; don’t be alarmed at the mild elevation of aminotransferase, we need to ask the doctor to analyze and observe, and review the aminotransferase, “two pairs of halves” and HBVDNA, to exclude other causes (non-hepatitis factors) caused by ALT ” mildly elevated”, and then we should not be alarmed at the mild elevation of aminotransferase. Mildly elevated”, and then decide when to start antiviral treatment; only if the hepatitis B virus is actively replicating (hepatitis B “two half” is “triple positive” or “triple positive”), and at the same time HBVDNA is “triple positive” or “triple positive”, and HBVDNA is “triple positive”. Only when hepatitis B virus replication is active (hepatitis B “two half” is “big triple positive” or “small triple positive”, at the same time, HBVDNA is positive and reaches a certain level) and the patient has a certain immune clearance response to the invading virus (usually manifested as ALT elevation, usually need ALT more than 2 times the normal value), then hepatitis B patients need to carry out active antiviral treatment. If the “threshold” of antiviral treatment is not reached, and the patient has the desire for treatment, liver puncture should be performed, and antiviral treatment can only be given after liver biopsy proves that the liver is really inflamed, or there is obvious hepatic fibrosis.