Percutaneous puncture for hepatic cysts is the most basic method of interventional treatment methods for hepatic cysts. In the 1970s, some experts started to drain liver cysts by puncture under ultrasound guidance, but the recurrence rate of simple puncture was high; in 1981, Bean et al. used to treat liver cysts successfully by injecting sclerosing agent-anhydrous alcohol after aspiration of cystic fluid by puncture under ultrasound guidance. This method greatly reduced the recurrence rate of simple puncture and drainage. Today, percutaneous puncture intervention for liver cysts has become a relatively safe, simple and effective treatment method; it can also be used in the treatment of liver cysts combined with infection. The treatment principle is: sclerosing agent can make the cyst wall epithelial cells protein coagulation denaturation, precipitation precipitation, dehydration and astringency, so that its biological activity disappears and lose the secretion function, and then promote the cyst wall adhesion, sclerosis closure, cyst cavity closure, cyst shrinkage gradually disappear. Percutaneous intervention has been recognized as one of the preferred methods for the treatment of congenital hepatic cysts, which generally requires ultrasound, CT or MRI guided puncture intervention, but the selection of cases is very important for the success or failure of interventional therapy. It is indicated for symptomatic cystic liver with compression symptoms of 5-10 cm in diameter, mainly larger cysts, who need to relieve symptoms; large cysts and patients with urgent treatment requirements. Contraindications: poor coagulation mechanism, allergy to sclerosing agent and those with large amount of ascites. Especially when the aspirated cystic fluid contains blood and bile, suggesting that the cyst may be connected with blood vessels and bile ducts, it is also not advisable to inject sclerosing agents such as anhydrous ethanol to avoid damaging the important duct system in the liver. It is easy for patients to accept; ④ can be repeated, and the efficacy is satisfactory, with a high efficiency of up to 90%; ⑤ flexible application, can be used alone or in combination with open surgery or laparoscopic surgery, to further improve the overall efficacy. Disadvantages: higher recurrence rate, often requiring multiple puncture injections, long overall treatment period, etc. The overall efficacy evaluation is still inferior to that of laparoscopic windowing.