The appearance of running water on the skin is considered to be oozing from the skin, which may be caused by eczema, herpes zoster, and fatty liquefaction of wounds. 1. eczema: eczema is a relatively common inflammatory skin disease, eczema can be manifested in the acute stage of erythema, corn size papules, papules, severe cases can appear small blisters, often fused into a piece, due to scratching to form a punctate vesicular surface, with obvious plasma exudate, so that the skin appears to be running and so on. 2. Herpes zoster: Herpes zoster is a skin disease mainly caused by the activation of varicella zoster virus, which mainly manifests unilateral, clustered blisters along the zonal distribution, accompanied by itching, pain, etc. After the blisters are broken, skin oozing and running water may appear. 3. Wound fat liquefaction: when the patient has skin breakage, especially the patients with fat hypertrophy, when the wound does not heal for a long time, there is necrosis of adipose tissue, liquefaction, there may be skin pus, oozing and so on. Skin oozing may also be contact dermatitis, pemphigus, herpetic pemphigoid, severe drug rash and other diseases, it is recommended that patients go to the regular hospital in a timely manner to consult a doctor for examination, a clear diagnosis and then targeted treatment. In life need to protect the skin, avoid scratching, and keep the local skin clean, dry and so on.