Some people often suddenly feel pain in the frontal joints at night, there will be redness and swelling, etc., and go to the hospital to check and find out that they have gout, so what kind of disease is gout? Is there any relationship between this disease and obesity? Can gastric bypass for weight loss surgery be an effective treatment? Gout is a common and complex type of arthritis disease, all ages may suffer from this disease, and found that the incidence of men than women. Commonly, patients with gout often experience sudden joint pain at night with a rapid onset of severe pain, edema, redness and inflammation in the joint area, which slowly decreases until the pain disappears and lasts for several days or weeks. Studies have shown that there are four general causes of gout: dietary reasons, obesity, the use of certain medications, and family history. Gout is not only a single disease, it can be associated with a variety of metabolic diseases such as obesity, hypertension, diabetes, and lipid metabolism disorders. Obesity is the main risk factor of gout, obesity not only increases the risk of gout, but also obese patients have a younger age of gout onset, and with the increase of BMI, the incidence of gout increases significantly and is proportional, especially high visceral fat of the human body also has a close relationship with ventilation. There are many people think that gout is because of the large intake of seafood and other foods, as long as the elimination of animal offal and lean meat intake, there will be no purine trouble, it seems that gout has nothing to do with obesity. However, medical statistics show that gout not only occurs mostly in obese patients, but the incidence of gout in obese patients is more than 50% higher than in others. However, once obese patients have reduced their weight and returned to their ideal weight, the incidence of gout is greatly reduced. Gastric bypass, as a type of weight loss surgery, is the ideal choice for weight loss. While ordinary weight loss methods are difficult to adhere to, have slow results, and may cause delays, the results after gastric bypass surgery are obvious. The surgery achieves weight loss by improving the reconstruction of the patient’s gastrointestinal system, reducing the secretion of hunger hormones, and shortening the absorption intestine, all at once, and also regulates the insulin secretion status and relieves insulin resistance. Not only is it a simple weight reduction procedure, but it can also treat gout and relieve various complications! Obesity is a high risk factor for gout and many chronic diseases, therefore, slightly obese people should control their weight and physical exercise to achieve weight loss, while those with higher BMI or already obese chronic diseases should actively lose weight and prioritize gastric bypass bariatric surgery if necessary.