Wrinkling of the white eyeball is usually a sign of conjunctival edema or conjunctival relaxation. Conjunctival edema is usually caused by local inflammation or eye fatigue, such as allergic conjunctivitis or bacterial conjunctivitis, according to the different causes of the choice of medication, after the edema is reduced, the symptoms of wrinkles will also be improved, and the recovery will be faster. Conjunctival laxity, usually seen in the elderly, is a degenerative change that occurs after ageing, this condition is usually in the early stages when the symptoms are not very obvious, such as not causing significant eye discomfort or foreign body sensation does not need to be treated, if these symptoms, you can consider surgery, such as conjunctival annuloplasty, the loose conjunctiva excision, can be effective in improving the symptoms.