Craniocerebral injury and cerebral hemorrhage often require decompression surgery by debridement to control intracranial pressure. After the surgery, the brain tissue at the debridement site is placed under the direct action of atmospheric pressure, which directly affects the brain tissue due to the lack of the protective effect of the skull, and the atmospheric pressure outside the skull directly damages the brain function. In addition, the temperature outside the cranium also directly affects the brain tissue, and too much cold and too much heat is not conducive to the recovery of neurological function. So, does cranial repair help in neurological recovery? It has been shown that there is a significant change in neurological function after cranial defect repair, and the earlier the cranial repair is performed, the better. First of all, it needs to have good biocompatibility to reduce post-operative complications; it also needs to have light weight and high strength to eliminate patients’ concern about force-free collapse after surgery; of course, aesthetic effect is also one of the most important aspects for patients to choose materials to restore the original appearance of craniomaxillofacial and to meet patients’ wish to shape their beauty at the same time. Fortunately, there is a kind of polyetheretherketone material with excellent performance, which can be used for cranial bone repair to achieve very good and ideal results. This polyetheretherketone material, also known as PEEK, is a special polymer material with very high biocompatibility, three-dimensional shaping, precise anastomosis of the defective bone window, and is comparable to autologous cranial bone in terms of elasticity, stiffness, insulation, and stability, making it a very good cranial repair material. We use this new material to repair patients with cranial defects and have received good feedback from patients.