Cranial defect is a common disease in neurosurgery. There are many clinical causes of cranial defects, such as car accidents, traffic accidents and debridement surgeries that have to be performed due to craniosynostosis, etc., which may cause cranial defects. This exposes the brain to external danger, destroys the stable intracranial environment, causes impaired blood circulation and cerebral crest fluid circulation, and affects the operation of various neurological functions, which is very harmful to the organism, sometimes even fatal. Therefore, once skull defect occurs, skull repair surgery is needed in time, so, among many skull repair materials, is it expensive to choose bionic bone as skull repair implant material? Since the last century, skull defect repair materials have been evolving, from the initial metal materials, acrylic resin, hydrocarbon apatite to the current widely used titanium mesh and the most advanced polyether ether ketone, metal materials, acrylic resin, hydrocarbon apatite and other materials have various problems and have been gradually eliminated; at present, the cost of titanium mesh materials widely used in clinical practice is generally around 30,000, of course, according to the size of the area The price varies; although the titanium mesh material is inexpensive, but there are also many disadvantages, such as metal materials do not insulate, postoperative discomfort, wear scalp leading to titanium mesh exposed, infection, etc.. In recent years, with the development of modern medical industry, polyetheretherketone as a new material is used in cranial defect surgery, which has good heat insulation, no adverse reaction, high strength, good protection; high histocompatibility, no rejection of infection, bone window adaptation, appropriate disposal of factors affecting aesthetics, such as subcutaneous free, flap transfer, myofascial flap with tip transfer, brow arch shaping, etc., with better postoperative cosmetic effect and many other However, due to many factors such as price, it has not been fully popularized in China yet. Several years ago, we took the lead in carrying out cranioplasty with polyether ether ketone peek material in China, and after years of exploration, we have continued to innovate and upgrade the technology at the same time. At present, polyetheretherketone peek material cranial repair and plastic surgery has completed four technical innovations, experienced and widely praised by patients with cranial defects and their families.