Chicken skin is the common name for what is clinically known as keratosis pilaris, and because of individual differences, there is no single most effective way to eliminate keratosis pilaris on the thighs. Keratosis pilaris generally does not require treatment, if there is a need for treatment, you can follow the doctor’s instructions to take topical medication (such as retinoic acid ointment, etc.), oral medication (such as vitamin A, etc.) and other forms of treatment. 1. Topical medication: apply retinoic acid ointment, urea ointment, salicylic acid ointment, etc. to the thigh lesions as prescribed by the doctor to soften or dissolve the keratin and improve the symptoms, and can be combined with the use of moisturizing creams to alleviate the local dryness of the skin. 2. Oral medication: This disease may be related to vitamin A deficiency, so patients can follow the doctor’s instructions to take oral vitamin A preparations to relieve symptoms, in addition to oral retinoids, to carry out the treatment. Keratosis pilaris is usually not harmful to the health of the organism, but if it is in the exposed area, it may affect the appearance of the person who has the need for treatment is recommended to go to the hospital in a timely manner, under the guidance of the doctor standardized treatment.