Generally cephalosporin antibiotics can be divided into four generations, for the first generation cephalosporin antibiotics, mainly for gram-positive bacteria is more effective, generally can be used for biliary tract infections. For the second and third generation cephalosporins, they are still mainly for gram-positive bacteria, but can be effective in antibacterial treatment for gram-negative bacteria. The cephalosporins of the fourth generation mainly target Gram-negative bacilli for anti-inflammatory treatment, so the cephalosporin antibiotics used are different depending on the patient’s disease. Cephalosporin antibiotics can be widely applied to infections in the biliary tract of patients, infections in the lungs and infections of Staphylococcus aureus and other strains of bacteria in other parts of the body, and is a more widely used antibiotic in clinical practice. In addition, for patients with colds and symptoms caused by bacterial colds, patients can be actively infused with cephalosporins, such as ceftriaxone sodium, and active treatment for about 5-7 days will achieve good results.