Kaposi’s sarcoma mainly presents with a rash of plaques, patches and nodules, with plaques considered to be the early stage of damage, patches the fully developed damage and nodules the most advanced damage. The rash is usually found on the extremities, especially the distal lower extremities, and presents as bluish-brown or reddish-brown plaques and nodules, which can break down in the late stage and can be followed by lymphatic edema of the lower extremities. In addition to the skin, subcutaneous lymph nodes are most frequently involved, accounting for about 10% of all cases, and presenting as enlarged lymph nodes. 10% of cases have visceral involvement, in the order of gastrointestinal tract, liver and lungs, abdominal lymph nodes and heart. In a few cases, there is only visceral damage without cutaneous manifestations, and the disease progresses slowly with a fair prognosis. The prognosis of AIDS-related Kaposi’s sarcoma is determined by AIDS itself.