A hepatic cyst, or cyst of the liver, is a “blister” in the liver. Hepatic cysts are a relatively common benign disease of the liver, and can be classified as congenital, parasitic, or non-parasitic. The majority of liver cysts are congenital, and most of them are caused by the developmental disorders of small intrahepatic bile ducts, while solitary liver cysts occur due to ectopic bile ducts. Acquired factors are rare, such as in pastoral areas, if people are infected with encapsulated cysticercosis, parasitic cysts will be produced in the liver. Another example is trauma, inflammation, and even tumors can also cause hepatic cysts, caused by increased secretion of a bile duct somewhere in the liver due to inflammation, edema, scarring or stone obstruction, or bile retention, mostly single, or late due to blunt contusion of the liver, resulting in central rupture. The lesioned cyst is filled with blood or bile and the envelope is fibrous tissue, which is a solitary pseudocyst. The cysts can be solitary, just one, as small as 0.2 cm, or as many as ten or dozens, or even one can be as large as several tens of centimeters. Patients with multiple hepatic cysts are sometimes combined with cysts of other internal organs, such as concomitant renal cysts, pulmonary cysts and occasionally pancreatic cysts and splenic cysts. The clinical manifestations vary with the location, size and number of cysts, as well as the presence or absence of compression of adjacent organs and complications. Physiological cysts do not affect liver function and do not develop into liver cancer, so they are usually ignored and only need to be reviewed regularly. However, if it grows too large and makes the patient feel uncomfortable, it can be treated. In order to prevent the cyst from growing again, a thin needle can be inserted into the cyst to extract the fluid from the cyst, and then pure alcohol can be injected to necrotize the cyst wall. If the cyst grows very large and the patient feels painful, open surgery can also be considered to remove the cyst together with the membrane of the cyst to solve the patient’s pain.