The steps from advanced pancreatic cancer to death range from mild pain to the development of complications such as pain and finally serious clinical symptoms such as coma. Due to the individual differences of patients, the stage before death is also different, which is roughly divided into 3 stages. 1. The first stage: advanced pancreatic cancer, i.e. pancreatic cancer cannot be cured, at this time, the patient survives with tumor, no serious symptoms, or only minor discomfort, such as minor abdominal pain, etc., at this time, the patient’s life can be self-care. 2. The second stage: at this stage, patients will have a series of complications of advanced pancreatic cancer, such as severe pain caused by pancreatic cancer, respiratory insufficiency, etc. Serious patients will also vomit blood, severe weight loss, jaundice and so on. 3. Third stage: patients will have serious clinical symptoms, such as coma, multi-organ failure, unstable blood pressure, etc., which is basically the last stage of life.