The skull has its own sacred mission in terms of human health, and it is relatively hard, but there are always some unavoidable factors in life that cause skull defects. Cranial defects will inevitably bring different degrees of health effects, so when the problem of cranial defects to face is to take the cranial bone repair surgery, only in this way to avoid more unnecessary damage. Many patients are concerned about how much cranial repair surgery will cost, which customized material is better, and other similar questions. First of all, regarding the cost of cranial bone repair surgery, it is an inexact value, which includes various costs, such as the cost of preoperative examination, hospitalization and surgical fees, and the surgical fee also includes the cost of surgical materials and so on. In addition, different patients have different conditions and different hospitals charge different rates, all of which will affect the cost of skull repair surgery. There are many factors that affect the cost of skull repair surgery, and the skull repair material chosen will be an important factor affecting the cost of skull repair surgery. A good cranial repair material will have better results and may cost a little more. Since ancient times, there are many materials used for skull repair, from the initial human bone, Plexiglas to the more widely used titanium mesh material. Titanium mesh may have certain advances and advantages over some of the materials used in the past, but there are also many problems. Clinical surgery has found that patients using titanium mesh for skull repair are extremely prone to postoperative infections, rejection reactions, and may even have titanium mesh exposure, so titanium mesh is not ideal for cranial bone repair surgery. At present, we use a new type of polymer material, i.e. polyether ether ether copper material, also called PEEK material, which has achieved quite good results in clinical surgery. PEEK material has incomparable advantages compared with every material in the past, it is a kind of material that can be customized in three dimensions, which can really restore the anatomical structure of the human cranium, and has excellent performances, which is comparable to the autologous cranium and basically does not cause rejection and infection problems. Basically, there is no problem of rejection and infection, and the use of PEEK material for cranial bone repair surgery will not affect various medical examinations in the future.