Children with Mycoplasma pneumoniae infection is generally not recommended to take azithromycin and cephalosporin at the same time, you need to strictly follow the doctor’s instructions for medication, to ensure symptomatic treatment, avoid blind application of antibiotic drugs. The most appropriate antibiotics for Mycoplasma pneumoniae infection in children are macrolides, with azithromycin common; cephalosporins belong to a kind of antibiotics, suitable for gram-negative bacilli, cocci and other pathogenic bacteria infections, and the role of Mycoplasma infections is minimal. Therefore, simultaneous administration of cephalosporin antibiotics is usually not recommended if there is no combination of other bacterial infections. For children, it is important to follow the doctor’s instructions, especially the use of antibiotics to avoid blind application. Antibiotics should be used only when indicated by the doctor. It is recommended that children with Mycoplasma pneumoniae infections should go to the hospital in time, under the guidance of the doctor for treatment, do not use drugs privately, so as not to cause danger.