The bladder pain after holding urine for a long time, the pain is reduced after urination and relieved within a short period of time can be observed first, the pain is still serious after urination or not relieved for a long period of time can be treated with medication, those who cannot urinate can be left with a urinary catheter. 1, rest, observation: if the pain is not serious and relief occurs within a short period of time after urination, you can first rest properly and be observed without treatment; 2, medication: if the pain symptoms are serious after urination, it is recommended Give anti-inflammatory painkillers for treatment within a short period of time. For example, oral fenbendazole or topical indomethacin suppositories, the pain in the bladder will be significantly improved in 1-2 hours. If the pain is still severe after 1-2 hours, and even other symptoms such as frequent urination, urgent urination and painful urination occur, a urinary tract infection is highly suspected, and it is recommended to improve the routine urine examination at the hospital in time. If a urinary tract infection is diagnosed, treatment with quinolone antibiotics, such as levofloxacin, which is commonly used in clinical practice, is recommended. If the patient is under 18 years old, or in the stage of pregnancy or breastfeeding, cephalosporin antibiotics, such as cefaclor, can be given for treatment; 3. Retained urinary catheter: Very few patients will have a long time to hold urine, thus unable to urinate, it is recommended to go to the emergency department of the hospital to place a catheter at this time, generally retained for 0.5-1 days. If the patient is an older male and is suspected of having combined prostatic hyperplasia, it is recommended that the urinary catheter be left in place for about 1 week. Patients themselves need to be aware of the dangers of holding urine and try not to hold it in. If you hold urine for a long time, the bladder will be in a highly filled state, just as muscle strain from prolonged, high-intensity physical exercise can produce damage to the bladder area. Holding urine for a long time may also sometimes cause bilateral ureteral orifice reflux, which can seriously cause hydronephrosis.