Mitochondrial disease is a genetic disorder that can be ruled out by prenatal genetic testing of the amniotic fluid. Once a mutation in the relevant gene is detected, the possibility of mitochondrial disease can be considered and the fetus can be induced to avoid the birth of a sick child. Mitochondrial disease can lead to impaired ATP production in the body and can result in brain and muscle dysfunction, both peripheral muscle intolerance and central nervous system symptoms, and prenatal genetic testing provides a basis for diagnosing such diseases.