Impotence, premature ejaculation and easy fatigue may be caused by Kidney Yin deficiency or Kidney Yang deficiency. Kidney yin deficiency refers to internal disturbance of deficiency heat and loss of kidney yin. Symptoms such as soreness and pain in the waist and knees, insomnia and dreaminess, emaciation, spermatorrhea and premature ejaculation in men will appear, thus manifesting the symptoms of impotence, premature ejaculation and easy fatigue. Kidney yang deficiency means that the organism loses its warmth and kidney yang is deficient, which will result in fatigue (mental exhaustion and physical weakness), coldness and coldness of limbs. Men will experience impotence, premature ejaculation and slippery semen. So Kidney-Yang deficiency may also cause symptoms of impotence, premature ejaculation and easy fatigue. Both kidney yin deficiency and kidney yang deficiency may cause impotence, premature ejaculation and easy fatigue, so when these symptoms appear, you should seek medical advice to find out the cause of the disease, and you need to treat the symptoms according to the different evidence of the disease.