1.Individual factors 1.Psychological factors: Although trauma and psychological imbalance cannot cause cancer, i.e., they cannot initiate cancer, but they can lower the immunity of the body and reduce the function of thymus, spleen and lymph nodes, so that the cancer cells that were suppressed can proliferate actively. 2.Age: benign ovarian tumors peak at the age of 30, and malignant ones peak at the age of 50. 3, Anatomical, tissue and embryonic factors: Although the ovary is small, it has great potential for tumor development because: (1) it is rich in developmental germinal epithelium, germ cells, mesenchymal tissue and embryonic residual tissue. (2) The perennial cycle is in flux and is easily affected and dysregulated. (3) Exposure to internal and external environment. (4) Menstruation and endogenous sex hormones: estrogenic grade elements cause cancer mainly in estrone. Estrogen in turn promotes the carcinogenic ability of methylcholanthrene. 5.Maternity and breastfeeding: Maternity can reduce the occurrence of ovarian cancer, although some are significant only after 4 or more births. 6.Obesity: Fat can store estrogen and slow down its normal metabolism. Excess fat can be transformed into estrone and methylcholanthrene. 7, various functions of the body. 8.Blood type: among ovarian patients, type O accounts for 40% and type A 44% 9.Other diseases: ovarian cancer with thyroid disease is 3 times higher than normal. Because of low iodine, the pituitary gland is enhanced and ovarian cancer is promoted. HIV, HCMV and rubella virus can cause cancer, but mumps virus and influenza virus can reduce the occurrence of ovarian cancer. 2.Other aflatoxin derivatives can cause ovarian cancer. 1, diet and nutrients: high fat intake can increase ovarian cancer by 50%, and drinking coffee for more than 40 years can increase ovarian cancer by 3.4 times. 2.Tobacco and alcohol: smoking 20 cigarettes a day will increase ovarian cancer slightly. 3, birth control measures: oral contraceptives can protect the ovaries and significantly reduce the incidence of ovarian cancer. Tubal sterilization can also greatly reduce the incidence of ovarian cancer. In the diagnosis and treatment of benign ovarian tumors, intraoperative dissection of the healthy ovary is required. Removal of the uterus can reduce cancer in the preserved ovaries. V. Human and social factors The prevalence of ovarian cancer has tripled in the last 40 years as the age has moved forward. The prevalence of ovarian cancer is higher in large cities than in medium-sized cities and remote areas. Environmental factors 80% of them are chemical, such as nitrosamines, coal tar, alkylating agents and chromium have carcinogenic effects. Low zinc and low iodine are also said to be prone to ovarian cancer. The RR of ovarian cancer among first-degree female relatives of ovarian cancer patients (mothers and daughters, sisters, etc.) is 4.53. The chance of ovarian cancer among women with family history of ovarian cancer is 1/6.