Do you know about rheumatoid arthritis?

  Rheumatoid arthritis is an autochthonous disease characterized by non-suppurative inflammation of joints and peri-articular tissues, often accompanied by extra-articular symptoms, hence the name rheumatoid disease. Synovial inflammation, exudate, cell proliferation, granuloma formation, destruction of cartilage and bone tissue, and finally joint ankylosis and dysfunction occur in the joint cavity. It mostly affects small joints, such as the hand, foot and wrist joints, and is often symmetrical and chronic, with temporary remission. The disease is considered to be autochthonous because of the multisystem damage and autoantibodies can be found in the serum. The age of onset is mostly between 20 and 40 years old, with more women than men. The lesions are symmetrical and often affect the metacarpophalangeal joints, wrists, shoulders, interphalangeal joints, ankles and knees. The joints are red, swollen, hot, painful, and have impaired movement.  1, joint symptoms: Morning stiffness is the first symptom of the joint, often appearing before the joint pain. Joint stiffness is painful and uncomfortable at the beginning of activity, and morning stiffness is reduced or disappears when joint activity increases. Morning stiffness of the joint is obvious in the morning and decreases in the afternoon.  2, extra-articular manifestations: is part of the systemic manifestations of rheumatoid arthritis or its complications. The joint lesions of this disease can cause disability, but not death, and extra-articular manifestations are often the cause of death from this disease. These include rheumatoid nodules, rheumatoid vasculitis, rheumatoid heart disease, and kidney damage.  Rheumatoid arthritis so far there is no specific treatment, still stay on the treatment of inflammation and sequelae, take a comprehensive treatment, most patients can get a certain degree of effectiveness.  The current treatment aims to: ① control inflammation of joints and other tissues to relieve symptoms; ② maintain joint function and prevent deformity; ③ repair damaged joints to reduce pain and restore function.  General treatment: Those with fever, joint swelling and pain, and systemic symptoms should rest in bed until the symptoms basically disappear. Activities should be gradually increased after two weeks of improvement to avoid prolonged bed rest leading to joint disuse and even joint ankylosis. Adequate protein and vitamins should be included in the diet, and a small amount of blood transfusion can be given to those with significant anemia.  Drug therapy: mainly includes non-steroidal anti-inflammatory drugs, gold preparations, penicillamine, chloroquine, levamisole, immunosuppressants, adrenal corticosteroids and tretinoin, etc.  Physical therapy: The purpose is to use heat therapy to increase local blood circulation and relax muscles to achieve anti-inflammatory, decongesting and analgesic effects, while using exercise to maintain and enhance joint function. Physical therapy methods include the following: hot water bags, hot baths, wax baths, infrared rays, etc. After physical therapy, massage is also used to improve local circulation and muscle spasm.  Prognosis: Generally speaking, most of the patients recover better if they are treated actively and comprehensively at an early stage. The rapid onset of the disease is better than the slow onset of the disease, and men are better than women. If only a few joints are involved and the systemic symptoms are mild, or if the joints are not symmetrically distributed, the course of the disease is often short. About 10% to 20% of patients become disabled due to untimely treatment. The disease does not directly cause death, but severe advanced cases may die from secondary infection.