Prevention of monkeypox virus includes preventing imported cases, protecting high-risk groups, and raising public awareness of protective measures. 1. Preventing the importation of monkeypox virus from overseas is one of the key measures at present. It is necessary to map the epidemic situation in the places where people enter the country and take appropriate testing measures, as well as to strengthen the pre-entry quarantine of live animals or animal products from overseas sources. 2. Close contacts, frontline medical workers, wildlife predators, etc. are high-risk groups in the monkeypox outbreak. Studies have shown that the smallpox vaccine is 85% effective as a preventive measure, so the smallpox vaccine can be considered to be used for the prevention of monkeypox in high-risk groups. 3. Popularize the knowledge of monkeypox virus and related diseases, enhance public awareness of high-risk factors and protective measures, and promote good personal hygiene and protective habits. If you are suspected to be infected with monkeypox virus, please go to the hospital in time to get a clear diagnosis with the help of your doctor to avoid delaying your condition.