The normal hepatitis B two-to-one test is a test to check whether the patient has hepatitis and whether antibodies are formed after the hepatitis B vaccination. If the patient’s blood is negative for hepatitis B surface antigen, it is necessary to look at whether the hepatitis B surface antibody is negative or positive and the level of antibody titers. If it is positive and the antibody titer is high, it is mostly considered to be the autoimmune protection mechanism formed after vaccination, and the patient is immune to the hepatitis B virus and is not susceptible to chronic viral hepatitis B infection. For hepatitis patients, the purpose of checking the hepatitis B two pairs of half, or hepatitis B three system is mainly to see whether the patient is a major or minor triple-positive. If the patient has no viral replication, the patient’s liver function is normal and can continue to be observed for six months or once a year. If the patient is a major triple-positive, this situation also requires further blood testing of hepatitis B DNA to see if the virus has replicated, if the virus has replicated and combined with elevated glutamic aminotransferase and glutamic oxalacetic aminotransferase, we should actively consider antiviral treatment.