Mycoplasma infection is a self-limiting disease, if the cough is still mild at night after discharge from the hospital, generally no treatment is needed; if the cough affects the rest, it is necessary to pay attention to whether it is combined with cough variant asthma, gastroesophageal reflux disease, etc., or it may be a post-infectious cough, and medication can be given to treat the symptoms. 1. Cough variant asthma: it is a special type of bronchial asthma, which often occurs in the morning and at night, and can be treated with bronchodilating therapy such as salbutamol and doxophylline. 2. Gastroesophageal reflux disease (GERD): cough symptoms occur due to the reflux of gastric contents that irritate the throat, which can be treated with drugs such as omeprazole and domperidone. 3. post-infectious cough: generally refers to the respiratory tract infection itself after the disappearance of acute symptoms, the cough is still prolonged, most often seen after a cold, can be relieved by itself, the cough can be given to the serious dextromethorphan and other symptomatic cough suppressant treatment. Mycoplasma infection is still a slight cough at night after discharge, there are other reasons, it is recommended to consult a doctor in a timely manner to clarify the cause, give targeted treatment, the above drugs need to be standardized under the guidance of a professional physician and pharmacist, rational application.