Cold is the most common acute upper respiratory tract infection, mostly caused by respiratory viral infections, and muscle and joint pain in the extremities is the most common symptom. Muscle and joint pain in the limbs occurs after a cold. Firstly, patients should pay attention to rest, prevent from getting cold, and drink more water appropriately. Second, light diet, strengthen nutrition, eat more fresh vegetables and fruits. Third, oral anti-cold drugs to improve cold symptoms and shorten the course of the cold, commonly used drugs are compound aminophenalkylamine capsules, ibuprofen extended-release tablets, Lianhua Qingfei capsule, etc.