Table 4 TNM staging of renal cell carcinoma, AJCC, 8th edition, 2017

Staging

Standard

Primary tumor (T)

TX

Primary tumor cannot be evaluated

T0

No evidence of primary tumor

T1

Tumor ≤ 7 cm in maximum diameter and confined to the kidney

T1a

Tumor largest diameter ≤ 4 cm and confined to the kidney

T1b

4cm < maximum tumor diameter ≤ 7cm and confined to the kidney

T2

Tumor > 7 cm in maximum diameter and confined to the kidney

T2a

7cm

T2b

Tumor confined to the kidney with a maximum diameter >10cm and confined to the kidney

T3

Tumor invades major veins or perinephric tissue but does not invade the ipsilateral adrenal gland and does not exceed the perinephric fascia

T3a

Tumor invading renal vein or its branching renal segmental veins, or invading renal pelvic system, or invading perirenal fat and/or sinus fat, but not exceeding perirenal fascia

T3b

Tumor invades the subphrenic vena cava

T3c

Tumor invading the vena cava superior to the diaphragm or invading the wall of the vena cava

T4

Tumor invades the perirenal fascia, including the ipsilateral adrenal gland adjacent to the tumor

NX

Regional lymph nodes could not be evaluated

N0

No metastasis in regional lymph nodes

N1

Regional lymph nodes with metastasis

M0

No distant metastases

M1

With distant metastases