From the onset of menstruation in the early teens, to pregnancy and childbirth in the twenties and thirties, to menopause in the fifties …… women’s lives always seem to be “in constant flux”. Menopause is an important health “watershed”. As the name implies, menopause refers to a woman’s last menstrual period. It is the cessation of menstruation due to the exhaustion of follicles in the ovaries, which no longer develop and secrete estrogen and cannot stimulate the growth of the endometrium. Menopause is a normal life event, and for ancient peoples, who did not live long on average, menopause even represented a “relief” for women, allowing them to finally stop having children endlessly. However, as modern life expectancy increases, women have a long life after menopause to face the risk of various diseases. As a result, it has become a health hurdle and has even given many women a “fear of menopause”. The essence of menopause is the lack of estrogen caused by the atrophy of ovarian function, which leads to a series of short and long-term hazards. When menopause occurs, most women experience flushing and hot flashes, palpitations, chest tightness and other vasodilatory dysfunctions, as well as psychoneurological symptoms such as insomnia, emotional instability and depression, and sexual desire and quality of sex life are also affected. More importantly, the loss of estrogen as a “protective umbrella” increases the incidence of cardiovascular disease, making it the leading cause of death in women over 65 years old. In addition, after menopause, a large amount of bone loss causes osteoporosis, resulting in a significant increase in the occurrence of fractures of the lumbar spine and hip bones. Menopause is a major life event and should be dealt with proactively to minimize its damage. “It is necessary for every woman who will face menopause to understand the concept of ‘window period’ for menopause management.” The Clinical Application Guidelines for Menopause Management and Hormone Supplementation Therapy issued by the Chinese Medical Association’s Obstetrics and Gynecology Section points out that the so-called “window period” refers to the early start of comprehensive life adjustment and health management within 10 years after menopause and before the age of 60. This window of time can determine the health of the next few decades. “The sooner you start menopause management, the better, no matter what measures you take, preferably within 5 years or even 3 years of menopause, take action. Therefore, for the inescapable menopause, women should first face it positively with the right mindset. When emotions are difficult to control, you can talk to your family to gain their understanding and tolerance, rather than “pinpointing”. You can also find something for yourself to do, such as photography, travel, dancing, etc., to help distract yourself and increase socialization. Secondly, at this stage, a healthy lifestyle can not be sloppy. In addition to regular work and rest, balanced diet, but also consciously strengthen exercise, smokers should immediately quit smoking, obese people to lose weight, etc.. Finally, seek medical help. Through regular medical checkups, you can keep abreast of your health condition; timely and reasonable estrogen supplementation treatment can effectively help relieve discomfort and prevent diseases.