The pain behind the knee after squatting for a while is mainly due to the strain on the biceps femoris, semitendinosus and semimembranosus muscles behind the knee during the squatting process, and the formation of a strain or a minor strain, which can cause significant pain. The following treatment measures are usually taken: First, it is important to keep the muscles behind the knee in a relaxed state, avoid posterior extension of the leg, and keep the leg warm and not cold, otherwise it will lead to further inflammation and swelling in this area, which is not conducive to recovery. Second, you can use a warm water bag for hot compresses, 3-5 times a day, 20-30 minutes each time, are able to effectively increase local blood circulation and promote the absorption of inflammatory metabolites. Thirdly, you can take oral non-steroidal anti-inflammatory painkillers, such as Nimesulide and Ibuprofen, to relieve local inflammation, reduce inflammatory edema and alleviate pain. Generally, after the above treatment, the symptoms will be significantly relieved in 1-2 days’ time.