Impetigo has five clinical manifestations of lesions, called common impetigo, impetigo maculans, deep impetigo, follicular impetigo, and staphylococcal scald-like skin syndrome. Here we will only talk about the most common clinical form of impetigo vulgaris. (1) It is a contagious skin disease caused by bacterial infection, commonly seen in children, in summer and autumn, and is characterized by “sores everywhere”. (2) It occurs mostly on exposed areas and starts as small erythematous spots or blisters, which quickly turn into pustules with very thin walls and yellow crusts after breaking down. (3) Since the lesions are only on the epidermis, they do not leave scars after healing. (4) The scab can fall off and heal in 1-2 weeks. Some severe cases can cause sepsis and acute glomerulonephritis. (5) Treatment is very simple, less lesions, the condition of mild external erythromycin ointment can be, a larger area, the condition of the heavy need to oral or intravenous application of antibiotics, preferred amoxicillin, penicillin allergy can be used erythromycin, azithromycin. Children should be cautious with the use of saxosin.