Palmar-plantar pustulosis, also known as chronic palmar-plantar pustular psoriasis, is a chronic periodic focal palmar-plantar, erythematous-based, sterile, small pustules with keratinized, scaly skin disease. The disease usually has no obvious factors. The development of the disease can also be associated with infections. For example, inflammation of the tonsils may be associated with the disease, and it is also thought that the disease is related to allergy to metallic elements such as mercury, copper, and tin. The lesions are often desquamated, and the scales subside leaving a smooth dark red surface. Small pustules are present underneath. The pustules can dry up, desquamate, and recur. Bacterial culture of the pustular fluid is negative. In addition to oral medication in the clinic, you can also use local treatment Topical application of various glucocorticoids have a better effect, to close bandage therapy is good, long after the use of reduced efficacy, you can add vitamin A acid ointment or tacalcitol ointment. At present, it has been reported that 308 excimer light treated patients with palmoplantar psoriasis 25 times, with an efficiency of 53.3%, and it is reported that 308 excimer light treatment of palmoplantar psoriasis has fast insightful effect, short course of treatment and few adverse reactions. (Journal of Clinical Dermatology 2006, 35, 2, 113. Han Ling et al. reported the clinical efficacy of 308 excimer light in the treatment of psoriasis vulgaris and palmoplantar psoriasis).