Blisters around the nose and mouth are not necessarily herpes, but may be impetigo, which is not necessarily around the nose and mouth, but can be on the trunk and extremities. Impetigo is a bacterial infection and herpes simplex is a viral infection, so they are treated very differently. Impetigo is a Staphylococcus aureus or streptococcal infection. High temperature, high humidity, trauma, scratching, and low immunity can trigger the disease. It is characterized by a high incidence in summer, is highly contagious, can be transmitted by contact, and is easily prevalent in groups of children. If the above characteristics are met, the clinical manifestation is a purulent blister, soon erosion, oozing, crusting, and new rashes appearing around it, this may be impetigo, not herpes, so do not apply “acyclovir cream”, it is not symptomatic, clinics and health centers are prone to make this mistake. The first time you see this, don’t treat it as herpes, don’t apply acyclovir cream, and don’t apply “baby cream”.