The current treatment of palmoplantar pustulosis can only achieve the recent effect and cannot prevent recurrence. 1.Topical treatment: glucocorticoid, retinoic acid cream, cortical facilitator, etc. 2.Systemic treatment: immunosuppressants, vitamin preparations, retinoic acid, antibiotics, immunomodulation, herbal treatment. 3.Physical therapy: PUVA (photochemotherapy), phototherapy, bath therapy. 4, the same disease at different stages of treatment sometimes completely different, the wrong treatment can sometimes aggravate the disease. Please go to the regular hospital for consultation and treatment.