Hepatitis B virus over 10,000 is considered high and is considered a serious condition. The normal value of hepatitis B virus is 10^2IU/mL (different test kits have some variability), while hepatitis B virus more than 10,000, that is, more than 10^4IU/mL, has exceeded the normal range more, is a serious situation. It is recommended that patients go to the hospital in time for hepatitis B virus DNA test to clarify the active degree of viral replication, and also need to be combined with hepatitis B five, liver function tests, liver ultrasound, CT and other tests to clarify the severity of the damage to the liver area, if there are liver function abnormalities or liver damage, follow the doctor’s instructions for antiviral treatment. Hepatitis B patients with a viral load of more than 10,000 are recommended to consult a doctor in time for further diagnosis and treatment under the guidance of a doctor.