Normal humans have 46 chromosomes. The normal male karyotype is 46XY. The normal female karyotype is 46XX. If your chromosomes do not turn out this way, they are abnormal. Chromosomal abnormalities are divided into numerical and structural abnormalities. Chromosomal number abnormalities include polyploidy (e.g. 96 chromosomes), haploidy (23 chromosomes), chimerism (e.g. 46XX/45XO) and simple number abnormalities:e.g. 21-trisomy, 45-XO, 47XXY, etc. Chromosome structural abnormalities include a wide variety of inversions, translocations (balanced translocations, Robertson translocations, complex translocations, etc.), insertions, duplications, deletions and chromosomal polymorphisms.