The whole process of kidney replacement surgery includes trimming the donor kidney, incising the right iliac fossa area, anastomosis, and suturing the abdominal wall. ⒈ donor kidney: the donor kidney will be cleaned up, remove the excess fatty tissue, trim the ureter and blood vessels, and maintain sufficient length and caliber for anastomosis during surgery. PEAK incision of the right iliac fossa area: the patient’s right iliac fossa area was made an oblique incision, and the skin, subcutaneous tissue, and abdominal muscle were sequentially incised to the extraperitoneum, exposing the external iliac artery of sufficient length. 3Anastomosis: put the well irrigated donor kidney into the iliac fossa, the renal artery and vein were anastomosed end to end with the vein in the internal ilium, and then washed with heparinized water to check whether the blood flow is smooth, and incised the mucosa of the bladder, enlarged the opening of the ureter, and sutured the opening of the ureter to the mucosa of the bladder. Singing and suturing the abdominal wall: at this time, observe that there is no sign of ischemic necrosis in the recovery of renal blood flow, and if the patient can produce continuous urine output, it means that the kidney has been successfully anastomosed, and the abdominal wall can be sutured sequentially to end the surgery. To sum up, patients with kidney disease should seek for medical treatment in time, and the kidney transplantation surgery must be done in regular hospitals and by professional doctors.