The principle of HPV treatment is “treat the disease, not the virus”, which means that treatment is only needed if the HPV virus is causing cytopathic lesions, not if it is not causing detectable disease. So, when HPV does cause a lesion, how should it be treated? Treatment of low-risk HPV infection lesions Low-risk infections mainly cause various types of warts in the genital tract, such as condyloma acuminatum. For small lesions, freezing, laser, or lesions can be treated with imiquimod cream, trichloroacetic acid solution, or ghost toxin ointment. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. If the lesions of genital warts are large, then medication alone is not effective, usually surgical excision (you can use electric knife or cold knife), and then the residual lesions can be removed with medication. Treatment of high-risk HPV infection High-risk viruses have oncogenomes E6 and E7 and may integrate into human cells to cause cancer (of course, this is a small percentage of infected individuals). When HPV high-risk type infection is detected, it is important to confirm whether the human tissue is diseased (various precancerous lesions or cancer) by means of TCT, colposcopy and biopsy. In the field of obstetrics and gynecology, precancerous lesions can occur in the vulva, vagina, and cervix due to HPV infection, and are especially common in the cervix. If a tissue biopsy reveals CIN grade 1, physical therapy such as laser or microwave is sufficient; if the lesion escalates to CIN 2, physical therapy alone is no longer sufficient and cervical loop electrosurgery (LEEP) is required; if the lesion progresses to CIN 3, cervical conization is required to determine if there is a more serious lesion. Cancerous lesions of the vulva and vagina are less common than those of the cervix, and treatment is usually surgical excision.