Whether hepatitis B virus quantification of 10 to the 8th power requires treatment needs to be judged in combination with other test indicators, clinical symptoms, family history and so on. Hepatitis B virus quantification of 8 times 10 is a relatively high level, but if liver function, liver ultrasound, alpha-fetoprotein, liver hardness, liver fibrosis tests are normal, this kind of patients can choose to review regularly without treatment. If these patients have abnormal liver function, or liver ultrasound, liver hardness test, suggesting liver fibrosis, cirrhosis, liver cancer and other changes, then antiviral treatment is needed. Tenofovir or entecavir can be used for treatment. Hepatitis B patients are advised to go to the hepatology department of the hospital and follow the doctor’s instructions.