If the male partner drinks and smokes and the female partner gets pregnant, whether the impact is mainly related to the frequency of the male partner’s drinking and smoking, if it is only an occasional drink, or a small amount of smoking, it should have very little impact on the male partner’s sperm, that is, the impact on pregnancy is also relatively small, but if the male partner smokes and drinks for a long time, the alcohol in the wine and the nicotine in the cigarette may have a certain impact on the quality of sperm, which may affect the quality of the embryo. This will affect the quality of the embryo and may lead to abnormal fetal development, miscarriage and premature birth. Therefore, during the preparation period, it is recommended that the male partner should not smoke and drink as much as possible to achieve the goal of eugenics, and the female partner should also take appropriate folic acid supplements in the first and second trimesters of pregnancy to prevent fetal neural tube development defects.