Cell activation cosmetic is a common cosmetic technique that increases the regeneration of cells in the face through the concept of cellular cosmetology to achieve cosmetic results. In addition to this, there are many claims that autologous cell activation cosmetic treatments can achieve wrinkle removal, fillers, and other effects. However, strictly speaking, there is no autologous cell activation cosmetic technology. Take wrinkle removal as an example, the wrinkles currently mentioned include two kinds, one is static wrinkles and the other is dynamic wrinkles. The first kind of dynamic wrinkles include crow’s feet, Kawasaki lines, head lines, these usually need to use drugs like botulinum toxin, so that the local muscles become calm, to achieve the effect of eliminating wrinkles; the second kind of depressed wrinkles, such as the decree line, this kind of need to fill, not necessarily need cell beauty methods, and the existing cells are not mature. Some consumers filled less than 1 year, hard lumps and hard nodules appeared, and some even had crazy growth of non-normal tissues. In summary, both adult stem cells and embryonic stem cells cannot be used directly for filling, and most of the commercially available cellular fillers are false advertisements, most of them use growth factors or liposuction methods, and finally they become fat fillers.